Summary

Nb ID
IAC
Insect Description
26and28 AMINOPEP_AD_CENTRAL PS50610 N

Aminopeptidase type M1 domains. These domains specifically describe regions of the M1 family of Metalloaminopeptidases.

Example : AMPN_MANSE (P91885)

56 AMINOPEP_AD_CTER PS50611 N
69 CARBOPEP_ABU PS50612 N

Overlap with SMART :Zn_carbopept and pfam :peptidase_M14  specific for subfamily ABU contains active sites

Example : CBPA3_RAT (P21961)

70 GALT PS50624 N

N-acetylgalactosaminyltransferase family. between the Glycosyl transferase (IPR001173) domain and the Ricin-type beta-trefoil lectin domain (PF00652).

 

Examples: GALT1_DROME, GALT3_CAEEL
73and86 DNA2NAM7 PS50613 N

NP_BIND_ATP associated domain ?

Overlap with SMART :DEXDc and TIGRFAM :put_DNA_helic
Found in regulators of non-sense transcripts helicases.

Examples : NAM7_YEAST, DNA2_YEAST, RENT1_HUMAN
168 BKAD PS50614 N

This domain is always found associated with the BTB domain and the Kelch repeat. A large number of proteins contain this arrangement of motif :  BTB=BKAD=80-100aa=KELCH repeats  (BTB without KELCH never show BKAD)

Overlap with pfam :BACK domain
Example : KELC_DROME (Q04652)
172 DYHC_AD5 PS50615 N

Very often found on the N-ter of pfam :Dynein_heavy between AAA5 and AAA6

Very often found on the N-ter of AAA1

Hyp : structurally these 2 domains interact.
Example DYHC_DROME(P37276)

211 DYHC_AD1 PS50616 N
189 NEUROPEP_STATIN2 PS50617 Y

Series of potentially related neuropeptides produced as a polyprotein Allostatin, Bombystatin, Helicostatin, Drostatin, etc.

Probably better defined as a PATTERN pat :neuropep_statin :

x(1,13)-[FYC]-[ASDGNHL]-F-G-[LVIM]-G-[KR]-R

cleaved after [LVIM] and amidated by the following G providing the amino group.

where the x(1,13) header gives the specificity of the neuropeptide A-type amide : [YFC]xFG

B-type amide : Wx6 ??

191 CHIPOLSAC_AD

PS50618

N

Always found C-ter of pfam :polysacch dacetylase and associated with a chitin binding domain

Example: Q8IQU1_DROME
202 RVTAD1 PS50620 N

Located between pfam :Exo_endo_phos and pfam :RVT.

Examples : O01419_BOMMO, O18558_AEDAE
229 RVTAD2 PS50621 Y

N-ter insect C-ter insect (and see urchin ?) specific 160-300aa C-ter of pfam :RVT (in the nucleic ac binding  endonuclease region of PO14_NASVI).

Examples: O01419_BOMMO, O18558_AEDAE
213 RVTAD3 PS50626 Y

C-terminus of RT_POL (PS50878) and Pfam: RVT_1 (PF00078).

Examples: O01419_BOMMO, O18558_AEDAE. Insect or arthropod (spiders) specific.
192 TPR_P4H PS50619 N

Found exclusively in Prolyl 4-hydrolase alpha related protein also called Procollagen-proline-2-oxoglutarate-4-dioxygenase alpha1 subunit

Always N-ter of SMART :P4Hc and pfam :2OG-FeII_Oxy

Overlapp with SSF :TPR-like

Hyp : involved in protein-protein interaction

Example: P4HA2_HUMAN (O15460)
250 TSP1_AD PS50622 N

Always found in ADAM-TS family. Usually between a TSP1 domain and right N-ter of the pfam :ADAM_spacer1

Example: ATS12_HUMAN (P58397)
210 INTEGRASE_AD_1 PS50625 N

Retrovirus-related Pol proteins Located at the of C-terminus of the domain Pfam: rve (PF00665), prf:INTEGRASE (PS50994) and the ipr: 4RNaseH_fold (IPR012337)

233 INTEGRASE_AD_2 PS50627 N
219 HA2XTND PS50623 N

Extension of pfam :HA2 going C-ter of RNA helicase family except for DEAH_box_HrpA family

Example : KZ_DROME(O46072), Q7PUF9_ANOGA