Fuente: http://kisac.cmb.ki.se/kisac/education/exercises/adv/ex_mult_align.html

Multiple alignment Exercise

Access the genbank/embl database, and search for some sequences for a multiple alignment.

(No ideas??..try these key-words: bHLH, tim44, vhl, tyrosine kinase, ETS, or some other favourite protein/DNA sequence.)

Copy these sequenes in FastA format (5 or 6...depending on their length!), and paste into a file for analysis.  Use the program CLUSTALW, MUSCLE AND t-COFFEE to conduct the multiple alignment.

a) What sequences did you use? (protein/dna?, names of gene)
b) What did the alignmentS show?
c) Were there any domains or regions of similarity between your squences?